The Neuro-Immune Method

Safeguarding your health properly is so much more than just taking supplements & running labs. At Pucci Wellness, we follow an integrated approach to functional medicine—designed to treat the unified system of your body including your brain, called The Neuro-Immune Method(TM)

With current medical research, we have discovered that the body is a complex collection of organs, systems and even bacterial colonies (the microbiome) that greatly influence each other.

And while standard treatments haven’t quite “caught up” yet with most of current science, functional medicine is outpacing the rest by connecting the dots on what is working and what is not.

Sadly, even most functional doctors still use the old model—treating symptoms by prescribing supplements using a cookie-cutter approach, when, in reality, it’s a systemic issue that needs to be addressed.

At Pucci Wellness we specialize in uncovering the hidden brain-immune drivers of chronic illness and guiding patients through a structured, high-touch program that restores lasting health, called The Neuro-Immune Method.

The Nervous System is Foundational

  • The nervous system is the master regulator of all other systems—digestion, hormones, detox, circulation, immune response.

  • When the Autonomic Nervous System (ANS) is out of balance (for example, when stuck in flight or fear mode), no amount of diet changes or supplements will “stick.”

  • Patients often have symptoms (constipation, reflux, brain fog, fatigue, dizziness, sleep issues) that are secondary to poor neural regulation, not just biochemical imbalance.

Your nervous system is like the operating system of a computer. It is the brains behind everything, much like the CEO of a highly complex and well-differentiated organization. If the operating system is glitching, or executive-level function doesn’t happen, it doesn’t matter how many new apps (supplements or diets) we install—they won’t run properly.

Autonomics Reveal Patterns of Resiliency

  • Heart Rate Variability testing provides a real-time, objective measurement of how well the ANS adapts to stress and recovers.

  • Unlike standard labs, HRV doesn’t just show a “snapshot”—it shows how resilient or fragile someone’s system is.

  • It validates symptoms patients feel but often can’t prove with conventional tests.

Your nervous system is like the operating system of a computer.
It is the brains behind everything, much like the CEO of a highly complex and well-differentiated organization.

If the operating system is glitching, or executive-level function is off, it won’t matter how many new apps (supplements or diets) we install—they won’t run properly.

What Makes the Neuro-Immune Method Successful?

Most practitioners:

  • Focus heavily on gut protocols, detox, or hormones.

  • Order extensive labs, but often miss why those labs are off.

  • Address symptoms at the biochemical or organ level only.

Our approach:

  • Starts with the command center—the nervous system.

  • Uses HRV and autonomic testing to uncover hidden dysfunction.

  • Includes a suite of lab tests focused on gut-brain-immune so that we can gather clinical insight about frequent culprits and pathways of inflammation.

  • Designs strategies that don’t just change lab values but restore control and adaptability across all body systems.

Most practitioners focus on chemistry—what’s too high or too low. I focus on circuitry & advanced pattern recognition—how the brain and nervous system run the show, responding to stressors & triggers as they interact with and feel their way through the world. When we calm the operating system, everything else—digestion, hormones, energy—has a chance to reset.”

dr pucci reviewing case file of motivated client

“I help patients with complex, unresolved health issues who have not found answers in conventional or surface-level functional medicine. With 35 years of clinical experience and advanced certifications in functional neurology and functional immunology, I specialize in uncovering the hidden brain–immune drivers of chronic illness and guiding patients through a structured, high-touch program that restores lasting health. My practice is not for everyone—it’s for those ready to invest in the right care to finally move forward.”

How the Neuro-Immune Method Works in Practice

Meet Jenny

Jenny had been doing everything “right.” She followed the protocols of a well-known functional medicine expert, changed her diet, and took multiple supplements. Yet she ended up in the ER with sudden left-sided abdominal pain, and her labs showed a spike in white blood cells (from 7 to 17). Her CT scan was negative, and she was told “nothing’s wrong.”

Meanwhile, she still struggled daily with inflamed thyroid nodules, throat pain, and difficulty swallowing. She was frightened and frustrated.


What Traditional Approaches Missed

  • Conventional medicine looked for a structural problem (CT, UTI screen).

  • Functional medicine often would have doubled down on gut protocols or diet restrictions.

  • Neither addressed the bigger picture: Jenny’s nervous system and immune system were in overload.


Applying the Neuro-Immune Method

Instead of starting with “more supplements” or “more food rules,” we applied the Neuro-Immune Method:

  1. Nervous System Assessment

    • We ran a Heart Rate Variability (HRV) test and an autonomic assessment to see how her nervous system was adapting.

    • Results showed Jenny was “stuck” in stress mode, with poor recovery capacity.

  2. Pattern Recognition

    • Her symptoms mapped into gut-brain inflammation and immune system overload patterns.

    • This explained why thyroid nodules stayed inflamed, why her digestion was reactive, and why her immune system spiked.

  3. Functional Testing

    • A comprehensive blood panel gave us clarity on thyroid, nutrient status, and inflammation markers.

    • A stool and microbiome test helped uncover hidden immune triggers.

    • We also learned about her phenotypic immune response and other personalized factors about her genetics
  1. Personalized Roadmap

    • By combining nervous system data with labs, Jenny finally had a clear picture of why her body was stuck.

    • Her roadmap included steps to restore parasympathetic tone, reduce stress physiology, support nutrient repair, and calm inflammation.


The Difference

Most programs would have focused on food elimination or supplement trials. And while these can be helpful, the Neuro-Immune Method showed Jenny that the problem wasn’t simply what she ate, but how her brain and nervous system were regulating her body under stress.

By treating the operating system (the nervous system), we gave her a way to break the cycle—something she hadn’t experienced before.

15 Minutes Could Change Your Life

Embrace the Future Of You.

If there’s a gap between where you are and how you want to feel, this call is the first bridge toward a better future.

Scroll to Top